The Pulmonary Extracellular Matrix Is a Bactericidal Barrier Against Haemophilus influenzae in Chronic Obstructive Pulmonary Disease (COPD): Implications for an in vivo Innate Host Defense Function of Collagen VI

Non-typeable Haemophilus influenzae (NTHi) is a Gram-negative human commensal commonly residing in the nasopharynx of preschool children. It occasionally causes upper respiratory tract infection such as acute otitis media, but can also spread to the lower respiratory tract causing bronchitis and pne...

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Main Authors: Suado M. Abdillahi, Ramesh Tati, Sara L. Nordin, Maria Baumgarten, Oskar Hallgren, Leif Bjermer, Jonas Erjefält, Gunilla Westergren-Thorsson, Birendra Singh, Kristian Riesbeck, Matthias Mörgelin
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01988/full