Protein phosphorylation in neurodegeneration: friend or foe?

Protein phosphorylation in neurodegeneration: friend or foe?

Protein misfolding and aggregation is a common hallmark in neurodegenerative disorders, including Alzheimer’s disease (AD), Parkinson’s disease (PD), and fronto-temporal dementia (FTD). In these disorders, the misfolding and aggregation of specific proteins occurs alongside neuronal degeneration in...

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Bibliographic Details
Main Authors: Sandra eTenreiro, Katrin eEckermann, Tiago F Outeiro
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-05-01
Series:Frontiers in Molecular Neuroscience
Subjects:
alpha-Synuclein
Phosphorylation
Parkinson’s disease
neurodegeneration
Alzheimer’s disease
tau
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2014.00042/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnmol.2014.00042/full

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