High-Yield Human Induced Pluripotent Stem Cell-Derived Monocytes and Macrophages Are Functionally Comparable With Primary Cells

High-Yield Human Induced Pluripotent Stem Cell-Derived Monocytes and Macrophages Are Functionally Comparable With Primary Cells

Macrophages are pivotal effectors of host immunity and regulators of tissue homeostasis. Understanding of human macrophage biology has been hampered by the lack of reliable and scalable models for cellular and genetic studies. Human induced pluripotent stem cell (hiPSC)-derived monocytes and macroph...

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Bibliographic Details
Main Authors: Di Cui, Alexandra Franz, Sophie A. Fillon, Linda Jannetti, Timo Isambert, Katrin Fundel-Clemens, Heinrich J. Huber, Coralie Viollet, Alexander Ghanem, Akira Niwa, Bernd Weigle, Stefan Pflanz
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
macrophages
monocytes
iPSC
differentiation
myeloid
Crispr/Cas
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.656867/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.656867/full

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