Currently Applied Molecular Assays for Identifying <i>ESR1</i> Mutations in Patients with Advanced Breast Cancer

Currently Applied Molecular Assays for Identifying <i>ESR1</i> Mutations in Patients with Advanced Breast Cancer

Approximately 70% of breast cancers, the leading cause of cancer-related mortality worldwide, are positive for the estrogen receptor (ER). Treatment of patients with luminal subtypes is mainly based on endocrine therapy. However, ER positivity is reduced and <i>ESR1</i> mutations play an...

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Bibliographic Details
Main Authors: Nuri Lee, Min-Jeong Park, Wonkeun Song, Kibum Jeon, Seri Jeong
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:International Journal of Molecular Sciences
Subjects:
estrogen receptor
<i>ESR1</i>
breast cancer
next-generation sequencing
droplet digital polymerase chain reaction
Online Access:https://www.mdpi.com/1422-0067/21/22/8807

Internet

https://www.mdpi.com/1422-0067/21/22/8807

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