Role of oxygen tension and genetic background during the epigenetic conversion of mouse fibroblasts into insulin secreting cells

Epigenetic cell conversion overcomes the stability of a mature cell phenotype transforming a somatic cell in an unlimited source of autologous cells of a different type. It is based on the exposure to a demethylating agent followed by an induction protocol. In our work we exposed mouse dermal fibrob...

Full description

Bibliographic Details
Main Authors: Alessandro Zenobi, Fulvio Gandolfi, Tiziana Anna Luisa Brevini
Format: Article
Language:English
Published: Università degli Studi di Milano 2015-07-01
Series:International Journal of Health, Animal Science and Food Safety
Online Access:http://riviste.unimi.it/index.php/haf/article/view/5127