Genes on distal chromosome 18 determine vulnerability to excitotoxic neurodegeneration following status epilepticus, but not striatal neurodegeneration induced by quinolinic acid

Previous studies have provided evidence that a quantitative trait locus (QTL) on the distal part of chromosome 18 (chr18) is a major determinant of vulnerability to hippocampal neurodegeneration following kainic acid (KA)-induced seizures in inbred mouse strains. We assessed excitotoxic vulnerabilit...

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Bibliographic Details
Main Authors: Jessica Pilar McLin, Leslie Michels Thompson, Aldons J. Lusis, Richard C. Davis, Oswald Steward
Format: Article
Language:English
Published: Elsevier 2008-03-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996107002264