Functional polymorphisms in PRODH are associated with risk and protection for schizophrenia and fronto-striatal structure and function.

Functional polymorphisms in PRODH are associated with risk and protection for schizophrenia and fronto-striatal structure and function.

PRODH, encoding proline oxidase (POX), has been associated with schizophrenia through linkage, association, and the 22q11 deletion syndrome (Velo-Cardio-Facial syndrome). Here, we show in a family-based sample that functional polymorphisms in PRODH are associated with schizophrenia, with protective...

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Bibliographic Details
Main Authors: Lucas Kempf, Kristin K Nicodemus, Bhaskar Kolachana, Radhakrishna Vakkalanka, Beth A Verchinski, Michael F Egan, Richard E Straub, Venkata A Mattay, Joseph H Callicott, Daniel R Weinberger, Andreas Meyer-Lindenberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-11-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2573019?pdf=render

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http://europepmc.org/articles/PMC2573019?pdf=render

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