Stress Modifies the Expression of Glucocorticoid-Responsive Genes by Acting at Epigenetic Levels in the Rat Prefrontal Cortex: Modulatory Activity of Lurasidone

Stress Modifies the Expression of Glucocorticoid-Responsive Genes by Acting at Epigenetic Levels in the Rat Prefrontal Cortex: Modulatory Activity of Lurasidone

Epigenetics is one of the mechanisms by which environmental factors can alter brain function and may contribute to central nervous system disorders. Alterations of DNA methylation and miRNA expression can induce long-lasting changes in neurobiological processes. Hence, we investigated the effect of...

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Bibliographic Details
Main Authors: Paola Brivio, Giulia Sbrini, Letizia Tarantini, Chiara Parravicini, Piotr Gruca, Magdalena Lason, Ewa Litwa, Chiara Favero, Marco Andrea Riva, Ivano Eberini, Mariusz Papp, Valentina Bollati, Francesca Calabrese
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
stress
epigenetic
DNA methylation
miRNA
GR-responsive genes
lurasidone
Online Access:https://www.mdpi.com/1422-0067/22/12/6197

Internet

https://www.mdpi.com/1422-0067/22/12/6197

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