Genetic mechanisms of Coxiella burnetii lipopolysaccharide phase variation.

Coxiella burnetii is an intracellular pathogen that causes human Q fever, a disease that normally presents as a severe flu-like illness. Due to high infectivity and disease severity, the pathogen is considered a risk group 3 organism. Full-length lipopolysaccharide (LPS) is required for full virulen...

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Bibliographic Details
Main Authors: Paul A Beare, Brendan M Jeffrey, Carrie M Long, Craig M Martens, Robert A Heinzen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-03-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC5843353?pdf=render