Deletion of B-cell translocation gene 2 (BTG2) alters the responses of glial cells in white matter to chronic cerebral hypoperfusion

Deletion of B-cell translocation gene 2 (BTG2) alters the responses of glial cells in white matter to chronic cerebral hypoperfusion

Abstract Background Subcortical ischemic vascular dementia, one of the major subtypes of vascular dementia, is characterized by lacunar infarcts and white matter lesions caused by chronic cerebral hypoperfusion. In this study, we used a mouse model of bilateral common carotid artery stenosis (BCAS)...

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Bibliographic Details
Main Authors: Kaoru Suzuki, Mitsuru Shinohara, Yoshihiro Uno, Yoshitaka Tashiro, Ghupurjan Gheni, Miho Yamamoto, Akio Fukumori, Akihiko Shindo, Tomoji Mashimo, Hidekazu Tomimoto, Naoyuki Sato
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Journal of Neuroinflammation
Subjects:
BCAS
Chronic hypoperfusion
White matter lesion
Astrocytes
Mac2-positive cells
Online Access:https://doi.org/10.1186/s12974-021-02135-w

Internet

https://doi.org/10.1186/s12974-021-02135-w

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