T Cell Response Toward Tissue-and Epidermal-Transglutaminases in Coeliac Disease Patients Developing Dermatitis Herpetiformis

T Cell Response Toward Tissue-and Epidermal-Transglutaminases in Coeliac Disease Patients Developing Dermatitis Herpetiformis

The reason why only few coeliac patients develop the cutaneous manifestation of the disease, named dermatitis herpetiformis (DH), is still unknown. Epidermal transglutaminase (TG3) has been described as the main autoantigen of humoral immunity in DH but the mechanisms leading to this autoimmune resp...

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Bibliographic Details
Main Authors: Marzia Caproni, Manuela Capone, Maria Caterina Rossi, Veronica Santarlasci, Laura Maggi, Alessio Mazzoni, Beatrice Rossettini, Daniela Renzi, Lavinia Quintarelli, Beatrice Bianchi, Alessandra Ninci, Gabriele Lami, Antonio Calabrò, Lorenzo Cosmi, Francesco Annunziato, Francesco Liotta
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Immunology
Subjects:
T lymphocytes (CD4+)
tissue transglutaminase (TG2)
epidermal transglutaminase
celiac disease
cross reactivity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.645143/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.645143/full

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