Molecular Evolution of the Protease Region in Norovirus Genogroup II

Molecular Evolution of the Protease Region in Norovirus Genogroup II

Noroviruses are a major cause of viral epidemic gastroenteritis in humans worldwide. The protease (Pro) encoded in open reading frame 1 (ORF1) is an essential enzyme for proteolysis of the viral polyprotein. Although there are some reports regarding the evolutionary analysis of norovirus GII-encodin...

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Bibliographic Details
Main Authors: Keita Ozaki, Yuki Matsushima, Koo Nagasawa, Jumpei Aso, Takeshi Saraya, Keisuke Yoshihara, Koichi Murakami, Takumi Motoya, Akihide Ryo, Makoto Kuroda, Kazuhiko Katayama, Hirokazu Kimura
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Microbiology
Subjects:
molecular evolution
norovirus
GII
bioinformatics
protease
negative selection
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.02991/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.02991/full

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