Corticotropin Releasing Factor Type 1 and 2 Receptor Signaling in the Medial Prefrontal Cortex Modulates Binge-Like Ethanol Consumption in C57BL/6J Mice

Corticotropin Releasing Factor Type 1 and 2 Receptor Signaling in the Medial Prefrontal Cortex Modulates Binge-Like Ethanol Consumption in C57BL/6J Mice

Corticotropin releasing factor (CRF) signaling via limbic CRF1 and 2 receptors (CRF1R and CRF2R, respectively) is known to modulate binge-like ethanol consumption in rodents. Though CRF signaling in the medial prefrontal cortex (mPFC) has been shown to modulate anxiety-like behavior and ethanol seek...

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Bibliographic Details
Main Authors: Stacey L. Robinson, Carlos A. Perez-Heydrich, Todd E. Thiele
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Brain Sciences
Subjects:
binge drinking
corticotropin releasing factor
corticotropin releasing hormone
mice
ethanol
alcohol
drinking in the dark
CRF1R
CRF2R
medial prefrontal cortex
Online Access:https://www.mdpi.com/2076-3425/9/7/171

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https://www.mdpi.com/2076-3425/9/7/171

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