Strategies to Extend Thrombolytic Time Window for Ischemic Stroke Treatment: An Unmet Clinical Need

To date, reperfusion with tissue plasminogen activator (tPA) remains the gold standard treatment for ischemic stroke. However, when tPA is given beyond 4.5 hours of stroke onset, deleterious effects of the drug ensue, especially, hemorrhagic transformation (HT), which causes the most significant mor...

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Bibliographic Details
Main Authors: Ike dela Peña, Cesar Borlongan, Guofang Shen, Willie Davis
Format: Article
Language:English
Published: Korean Stroke Society 2017-01-01
Series:Journal of Stroke
Subjects:
Online Access:http://www.j-stroke.org/upload/pdf/jos-2016-01515.pdf