Resveratrol induces premature senescence in lung cancer cells via ROS-mediated DNA damage.

Resveratrol (RV) is a natural component of red wine and grapes that has been shown to be a potential chemopreventive and anticancer agent. However, the molecular mechanisms underlying RV's anticancer and chemopreventive effects are incompletely understood. Here we show that RV treatment inhibit...

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Bibliographic Details
Main Authors: Hongmei Luo, Aimin Yang, Bradley A Schulte, Michael J Wargovich, Gavin Y Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3606183?pdf=render