Brownian dynamics simulations of the interactions between lactate dehydrogenase (LDH) and G- or F-Actin. Part I: Muscle and heart homo-isoforms

Brownian dynamics simulations of the interactions between lactate dehydrogenase (LDH) and G- or F-Actin. Part I: Muscle and heart homo-isoforms

Glycolytic enzymes may compartment in cells by binding to cytoskeletal structures. One potentially important step in compartmentation is the binding of the cytoskeletal protein F-actin by lactate dehydrogenase (LDH). Brownian dynamics (BD) simulations of LDH interacting with G- or F-actin provided f...

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Bibliographic Details
Main Authors: Eric N. Njabon, Issofa Patouossa, Kristine L. Carlson, Stephen L. Lowe, Neville Y. Forlemu, Kathryn A. Thomasson
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Scientific African
Subjects:
Brownian dynamics
Free energy
Protein-protein interactions
Glycolytic enzymes
Electrostatic interactions
Online Access:http://www.sciencedirect.com/science/article/pii/S2468227620302489

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http://www.sciencedirect.com/science/article/pii/S2468227620302489

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