Cryo-EM analysis of the post-fusion structure of the SARS-CoV spike glycoprotein

The spike (S) protein of coronaviruses is responsible for receptor recognition and the fusion between the viral membrane and the of cell host membrane. Here the authors report a cryo-EM structure of SARS-CoV post-fusion S2 trimer, providing insights into the fusion mechanism that could be useful for...

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Bibliographic Details
Main Authors: Xiaoyi Fan, Duanfang Cao, Lingfei Kong, Xinzheng Zhang
Format: Article
Language:English
Published: Nature Publishing Group 2020-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-17371-6