Prognostic Significance of Carbonic Anhydrase IX Expression in Cancer Patients: a Meta-analysis

Prognostic Significance of Carbonic Anhydrase IX Expression in Cancer Patients: a Meta-analysis

Hypoxia is a characteristic of many solid tumors and an adverse prognostic factor for treatment outcome. Hypoxia increases the expression of carbonic anhydrase IX, an enzyme that is predominantly found on tumor cells and is involved in maintaining the cellular pH balance. Many clinical studies inves...

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Bibliographic Details
Main Authors: Simon J.A. Van Kuijk, Ala eYaromina, Ruud eHouben, Raymon eNiemans, Philippe eLambin, Ludwig J. Dubois
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-03-01
Series:Frontiers in Oncology
Subjects:
Cancer
Meta-analysis
hypoxia
prognosis
Carbonic Anhydrase IX
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2016.00069/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fonc.2016.00069/full

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