Passive experimental autoimmune encephalomyelitis in C57BL/6 with MOG: evidence of involvement of B cells.

Experimental autoimmune encephalomyelitis (EAE) is the most relevant animal model to study demyelinating diseases such as multiple sclerosis. EAE can be induced by active (active EAE) or passive (at-EAE) transfer of activated T cells in several species and strains of rodents. However, histological f...

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Bibliographic Details
Main Authors: Francesco Mannara, Tony Valente, Josep Saura, Francesc Graus, Albert Saiz, Beatriz Moreno
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3530560?pdf=render