Prediction of Drug–Target Interaction Networks from the Integration of Protein Sequences and Drug Chemical Structures

Knowledge of drug–target interaction (DTI) plays an important role in discovering new drug candidates. Unfortunately, there are unavoidable shortcomings; including the time-consuming and expensive nature of the experimental method to predict DTI. Therefore, it motivates us to develop an effective co...

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Bibliographic Details
Main Authors: Fan-Rong Meng, Zhu-Hong You, Xing Chen, Yong Zhou, Ji-Yong An
Format: Article
Language:English
Published: MDPI AG 2017-07-01
Series:Molecules
Subjects:
DTI
RVM
PCA
Online Access:https://www.mdpi.com/1420-3049/22/7/1119