GST-4-Dependent Suppression of Neurodegeneration in C. elegans Models of Parkinson’s and Machado-Joseph Disease by Rapeseed Pomace Extract Supplementation

GST-4-Dependent Suppression of Neurodegeneration in C. elegans Models of Parkinson’s and Machado-Joseph Disease by Rapeseed Pomace Extract Supplementation

Genetic mutations and aging-associated oxidative damage underlie the onset and progression of neurodegenerative diseases, like Parkinson’s disease (PD) and Machado-Joseph disease (MJD). Natural products derived from plants have been regarded as important sources of novel bioactive compounds to count...

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Bibliographic Details
Main Authors: Franziska Pohl, Andreia Teixeira-Castro, Marta Daniela Costa, Victoria Lindsay, Juliana Fiúza-Fernandes, Marie Goua, Giovanna Bermano, Wendy Russell, Patrícia Maciel, Paul Kong Thoo Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Neuroscience
Subjects:
rapeseed (canola) pomace
C. elegans
Parkinson’s disease
Machado-Joseph disease
Spinocerebellar ataxia 3
antioxidant
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.01091/full

Internet

https://www.frontiersin.org/article/10.3389/fnins.2019.01091/full

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