Nucleolar and spindle associated protein 1 promotes the aggressiveness of astrocytoma by activating the Hedgehog signaling pathway

Nucleolar and spindle associated protein 1 promotes the aggressiveness of astrocytoma by activating the Hedgehog signaling pathway

Abstract Background The prognosis of human astrocytoma is poor, and the molecular alterations underlying its pathogenesis still needed to be elucidated. Nucleolar and spindle associated protein 1 (NUSAP1) was observed in several types of cancers, but its role in astrocytoma remained unknown. Methods...

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Bibliographic Details
Main Authors: Xianqiu Wu, Benke Xu, Chao Yang, Wentao Wang, Dequan Zhong, Zhan Zhao, Longshuang He, Yuanjun Hu, Lili Jiang, Jun Li, Libing Song, Wei Zhang
Format: Article
Language:English
Published: BMC 2017-09-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Astrocytoma
NUSAP1
GLI1
Aggressiveness
Hedgehog pathway
Online Access:http://link.springer.com/article/10.1186/s13046-017-0597-y

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http://link.springer.com/article/10.1186/s13046-017-0597-y

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