WARBURG EFFECT AND TRANSLOCATION-INDUCED GENOMIC INSTABILITY: TWO YEAST MODELS FOR CANCER CELLS

WARBURG EFFECT AND TRANSLOCATION-INDUCED GENOMIC INSTABILITY: TWO YEAST MODELS FOR CANCER CELLS

Yeast has been established as an efficient model system to study biological principles underpinning human health. In this review we focus on yeast models covering two aspects of cancer formation and progression i) the activity of pyruvate kinase (PK), which recapitulates metabolic features of cancer...

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Bibliographic Details
Main Authors: Valentina eTosato, Nana-Maria eGrüning, Michael eBreitenbach, Remigiusz eArnak, Markus eRalser, Carlo Vito Bruschi
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-01-01
Series:Frontiers in Oncology
Subjects:
Aneuploidy
Chromosomes
Cancer
yeast
genome stability
double-strand break
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2012.00212/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fonc.2012.00212/full

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