β-Sitosterol Protects against Carbon Tetrachloride Hepatotoxicity but not Gentamicin Nephrotoxicity in Rats via the Induction of Mitochondrial Glutathione Redox Cycling

β-Sitosterol Protects against Carbon Tetrachloride Hepatotoxicity but not Gentamicin Nephrotoxicity in Rats via the Induction of Mitochondrial Glutathione Redox Cycling

Previous findings have demonstrated that β-sitosterol (BSS), an active component of Cistanches Herba, protected against oxidant injury in H9c2 cardiomyocytes and in rat hearts by enhancing mitochondrial glutathione redox cycling, possibly through the intermediacy of mitochondrial reactive oxygen spe...

Full description

Bibliographic Details
Main Authors: Hoi-Shan Wong, Ji-Hang Chen, Pou-Kuan Leong, Hoi-Yan Leung, Wing-Man Chan, Kam-Ming Ko
Format: Article
Language:English
Published: MDPI AG 2014-10-01
Series:Molecules
Subjects:
Cistanches Herba
β-sitosterol
carbon tetrachloride hepatotoxicity
gentamicin nephrotoxicity
glutathione redox cycling
mitochondria
Online Access:http://www.mdpi.com/1420-3049/19/11/17649

Internet

http://www.mdpi.com/1420-3049/19/11/17649

Similar Items