Arsenite selectively inhibits mouse bone marrow lymphoid progenitor cell development in vivo and in vitro and suppresses humoral immunity in vivo.

It is known that exposure to As(+3) via drinking water causes a disruption of the immune system and significantly compromises the immune response to infection. The purpose of these studies was to assess the effects of As(+3) on bone marrow progenitor cell colony formation and the humoral immune resp...

Full description

Bibliographic Details
Main Authors: Peace C Ezeh, Fredine T Lauer, Debra MacKenzie, Shea McClain, Ke Jian Liu, Laurie G Hudson, A Jay Gandolfi, Scott W Burchiel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3979857?pdf=render