Loss of Mitochondrial AAA Proteases AFG3L2 and YME1L Impairs Mitochondrial Structure and Respiratory Chain Biogenesis

Loss of Mitochondrial AAA Proteases AFG3L2 and YME1L Impairs Mitochondrial Structure and Respiratory Chain Biogenesis

Mitochondrial protein quality control is crucial for the maintenance of correct mitochondrial homeostasis. It is ensured by several specific mitochondrial proteases located across the various mitochondrial subcompartments. Here, we focused on characterization of functional overlap and cooperativity...

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Bibliographic Details
Main Authors: Jana Cesnekova, Marie Rodinova, Hana Hansikova, Jiri Zeman, Lukas Stiburek
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:International Journal of Molecular Sciences
Subjects:
mitochondria
protease
AFG3L2
YME1L
AAA complex
Online Access:https://www.mdpi.com/1422-0067/19/12/3930

Internet

https://www.mdpi.com/1422-0067/19/12/3930

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