The Genomic Characteristics of ALK Fusion Positive Tumors in Chinese NSCLC Patients

The Genomic Characteristics of ALK Fusion Positive Tumors in Chinese NSCLC Patients

Anaplastic lymphoma kinase (ALK) fusion events account for ~3–7% genetic alterations in patients with non-small cell lung cancer (NSCLC). In this study, we identified the ALK fusion patterns and a novel ALK fusion partner in 44 ALK positive NSCLC patients using a customized HapOncoCDx panel, and ide...

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Bibliographic Details
Main Authors: Shaokun Liu, Tanxiao Huang, Ming Liu, Wenlong He, YingShen Zhao, Lizhen Yang, Yingjiao Long, Dandan Zong, Huihui Zeng, Yuanyuan Liu, Wenting Liao, Jingxian Duan, Subo Gong, Shifu Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Oncology
Subjects:
NSCLC
ALK
NGS—next generation sequencing
copy number aberrations
genomic landscape
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.00726/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2020.00726/full

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