Transcriptional Suppression of miR-7 by MTA2 Induces Sp1-Mediated KLK10 Expression and Metastasis of Cervical Cancer

MTA2 is involved in tumor proliferation and metastasis. However, the role of MTA2 in cervical cancer thus far has not been identified. In this study, we report that elevated expression of MTA2 negatively correlates with Kallikrein-10 (KLK10) expression and poor prognosis of cervical cancer patients....

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Bibliographic Details
Main Authors: Chia-Liang Lin, Tsung-Ho Ying, Shun-Fa Yang, Shih-Wei Wang, Shih-Ping Cheng, Jie-Jen Lee, Yi-Hsien Hsieh
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
Sp1
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253120301177