Adenovirus-mediated anti-AEG-1 ScFv expression driven by stathmin promoter inhibits tumor growth in cervical cancer

Adenovirus-mediated anti-AEG-1 ScFv expression driven by stathmin promoter inhibits tumor growth in cervical cancer

Abstract Background Astrocyte-elevated gene-1 (AEG-1) is over-expressed in many cancer cells and has multiple key functions in tumor initiation and progression. Currently, targeted-AEG-1 siRNA is one of the most common techniques to down-regulate AEG-1 expression, but the lack of tumor specificity a...

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Bibliographic Details
Main Authors: Min Long, Fang Lin, Xi Wang, Xi Chen, Li Liu, Huizhong Zhang, Ke Dong
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Cancer Cell International
Subjects:
AEG-1
ScFv
Adenovirus
Stathmin promoter
Cervical cancer
Online Access:http://link.springer.com/article/10.1186/s12935-020-1159-5

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http://link.springer.com/article/10.1186/s12935-020-1159-5

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