A gene profiling deconvolution approach to estimating immune cell composition from complex tissues

Abstract Background A new emerged cancer treatment utilizes intrinsic immune surveillance mechanism that is silenced by those malicious cells. Hence, studies of tumor infiltrating lymphocyte populations (TILs) are key to the success of advanced treatments. In addition to laboratory methods such as i...

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Bibliographic Details
Main Authors: Shu-Hwa Chen, Wen-Yu Kuo, Sheng-Yao Su, Wei-Chun Chung, Jen-Ming Ho, Henry Horng-Shing Lu, Chung-Yen Lin
Format: Article
Language:English
Published: BMC 2018-05-01
Series:BMC Bioinformatics
Online Access:http://link.springer.com/article/10.1186/s12859-018-2069-6