Staphylococcus aureus Promotes Smed-PGRP-2/Smed-setd8-1 Methyltransferase Signalling in Planarian Neoblasts to Sensitize Anti-bacterial Gene Responses During Re-infection

Staphylococcus aureus Promotes Smed-PGRP-2/Smed-setd8-1 Methyltransferase Signalling in Planarian Neoblasts to Sensitize Anti-bacterial Gene Responses During Re-infection

Little is known about how organisms exposed to recurrent infections adapt their innate immune responses. Here, we report that planarians display a form of instructed immunity to primo-infection by Staphylococcus aureus that consists of a transient state of heightened resistance to re-infection that...

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Bibliographic Details
Main Authors: Cedric Torre, Prasad Abnave, Landry Laure Tsoumtsa, Giovanna Mottola, Catherine Lepolard, Virginie Trouplin, Gregory Gimenez, Julie Desrousseaux, Stephanie Gempp, Anthony Levasseur, Laetitia Padovani, Emmanuel Lemichez, Eric Ghigo
Format: Article
Language:English
Published: Elsevier 2017-06-01
Series:EBioMedicine
Subjects:
Neoblasts
Planarians
S. aureus
PGRP-2
sted8-1
Instructed immunity
Stem cells
Online Access:http://www.sciencedirect.com/science/article/pii/S235239641730186X

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http://www.sciencedirect.com/science/article/pii/S235239641730186X

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