Three epitope-distinct human antibodies from RenMab mice neutralize SARS-CoV-2 and cooperatively minimize the escape of mutants

Three epitope-distinct human antibodies from RenMab mice neutralize SARS-CoV-2 and cooperatively minimize the escape of mutants

Abstract Coronavirus disease 2019 (COVID-19), a pandemic disease caused by the newly emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused more than 3.8 million deaths to date. Neutralizing antibodies are effective therapeutic measures. However, many naturally occurring m...

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Bibliographic Details
Main Authors: Jianhui Nie, Jingshu Xie, Shuo Liu, Jiajing Wu, Chuan Liu, Jianhui Li, Yacui Liu, Meiyu Wang, Huizhen Zhao, Yabo Zhang, Jiawei Yao, Lei Chen, Yuelei Shen, Yi Yang, Hong-Wei Wang, Youchun Wang, Weijin Huang
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Cell Discovery
Online Access:https://doi.org/10.1038/s41421-021-00292-z

Internet

https://doi.org/10.1038/s41421-021-00292-z

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