Electrophysiological Characterization of Regular and Burst Firing Pyramidal Neurons of the Dorsal Subiculum in an Angelman Syndrome Mouse Model

Electrophysiological Characterization of Regular and Burst Firing Pyramidal Neurons of the Dorsal Subiculum in an Angelman Syndrome Mouse Model

Angelman syndrome (AS) is a debilitating neurogenetic disorder characterized by severe developmental delay, speech impairment, gait ataxia, sleep disturbances, epilepsy, and a unique behavioral phenotype. AS is caused by a microdeletion or mutation in the maternal 15q11-q13 chromosome region contain...

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Bibliographic Details
Main Authors: Prudhvi Raj Rayi, Hanoch Kaphzan
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Angelman syndrome
patch-clamp electrophsyiology
hippocampus
burst firing neurons
dorsal subiculum
mouse model
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2021.670998/full

Internet

https://www.frontiersin.org/articles/10.3389/fncel.2021.670998/full

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