Cryo-EM of nucleosome core particle interactions in trans

Abstract Nucleosomes, the basic unit of chromatin, are repetitively spaced along DNA and regulate genome expression and maintenance. The long linear chromatin molecule is extensively condensed to fit DNA inside the nucleus. How distant nucleosomes interact to build tertiary chromatin structure remai...

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Bibliographic Details
Main Authors: Silvija Bilokapic, Mike Strauss, Mario Halic
Format: Article
Language:English
Published: Nature Publishing Group 2018-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-25429-1