In Silico<i> </i>Optimization of Fiber-Shaped Aerosols in Inhalation Therapy for Augmented Targeting and Deposition across the Respiratory Tract

In Silico<i> </i>Optimization of Fiber-Shaped Aerosols in Inhalation Therapy for Augmented Targeting and Deposition across the Respiratory Tract

Motivated by a desire to uncover new opportunities for designing the size and shape of fiber-shaped aerosols towards improved pulmonary drug delivery deposition outcomes, we explore the transport and deposition characteristics of fibers under physiologically inspired inhalation conditions in silico,...

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Bibliographic Details
Main Authors: Lihi Shachar-Berman, Saurabh Bhardwaj, Yan Ostrovski, Prashant Das, Pantelis Koullapis, Stavros Kassinos, Josué Sznitman
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Pharmaceutics
Subjects:
in silico simulations
computational fluid dynamics
inhalation therapy
aerosols
fibers
respiratory tract
Online Access:https://www.mdpi.com/1999-4923/12/3/230

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https://www.mdpi.com/1999-4923/12/3/230

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