JARID2 and the PRC2 complex regulate skeletal muscle differentiation through regulation of canonical Wnt signaling

Abstract Background JARID2 is a non-catalytic member of the polycomb repressive complex 2 (PRC2), which is known to regulate developmental target genes in embryonic stem cells. Here, we provide mechanistic insight into the modulation of Wnt signaling by JARID2 during murine skeletal muscle different...

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Bibliographic Details
Main Authors: Abhinav Adhikari, Judith Davie
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Epigenetics & Chromatin
Subjects:
Wnt
Online Access:http://link.springer.com/article/10.1186/s13072-018-0217-x