Mechanisms of protein-folding diseases at a glance
For a protein to function appropriately, it must first achieve its proper conformation and location within the crowded environment inside the cell. Multiple chaperone systems are required to fold proteins correctly. In addition, degradation pathways participate by destroying improperly folded protei...
Main Authors: | Julie S. Valastyan, Susan Lindquist |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2014-01-01
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Series: | Disease Models & Mechanisms |
Subjects: | |
Online Access: | http://dmm.biologists.org/content/7/1/9 |
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