Mathematical modeling of dormant cell formation in growing biofilm

Understanding the dynamics of dormant cells in microbial biofilms, in which the bacteria are embedded in extracellular matrix, is important for developing successful antibiotic therapies against pathogenic bacteria. Although some of the molecular mechanisms leading to bacterial persistence have been...

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Bibliographic Details
Main Authors: Kotaro eChihara, Shinya eMatsumoto, Yuki eKagawa, Satoshi eTsuneda
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-05-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00534/full