Rewiring MAP kinases in Saccharomyces cerevisiae to regulate novel targets through ubiquitination

Rewiring MAP kinases in Saccharomyces cerevisiae to regulate novel targets through ubiquitination

Evolution has often copied and repurposed the mitogen-activated protein kinase (MAPK) signaling module. Understanding how connections form during evolution, in disease and across individuals requires knowledge of the basic tenets that govern kinase-substrate interactions. We identify criteria suffic...

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Bibliographic Details
Main Authors: Benjamin Groves, Arjun Khakhar, Cory M Nadel, Richard G Gardner, Georg Seelig
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-08-01
Series:eLife
Subjects:
MAP Kinase
kinase signaling
synthetic biology
ubiquitin
Online Access:https://elifesciences.org/articles/15200

Internet

https://elifesciences.org/articles/15200

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