Downregulation of miR-491-5p promotes neovascularization after traumatic brain injury

Downregulation of miR-491-5p promotes neovascularization after traumatic brain injury

MicroRNA-491-5p (miR-491-5p) plays an important role in regulating cell proliferation and migration; however, the effect of miR-491-5p on neovascularization after traumatic brain injury remains poorly understood. In this study, a controlled cortical injury model in C57BL/6 mice and an oxygen-glucose...

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Bibliographic Details
Main Authors: Wei Tang, Zong-Duo Guo, Wei-Na Chai, Dong-Lin Du, Xiao-Min Yang, Lang Cao, Hong Chen, Chao Zhou, Chong-Jie Cheng, Xiao-Chuan Sun, Zhi-Jian Huang, Jian-Jun Zhong
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2022-01-01
Series:Neural Regeneration Research
Subjects:
brain injury; cell migration; cell proliferation; endothelial cell; hypoxia-inducible factor-1 alpha; metallothionein 2; microrna; neovascularization; neurons; vascular endothelial growth factor
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2022;volume=17;issue=3;spage=577;epage=586;aulast=Tang

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2022;volume=17;issue=3;spage=577;epage=586;aulast=Tang

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