CRF2 signaling is a novel regulator of cellular adhesion and migration in colorectal cancer cells.

Stress has been proposed to be a tumor promoting factor through the secretion of specific neuromediators, such as Urocortin2 and 3 (Ucn2/3), however its role in colorectal cancer (CRC) remains elusive. We observed that Ucn2/3 and their receptor the Corticotropin Releasing Factor receptor 2 (CRF2) we...

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Bibliographic Details
Main Authors: Benjamin Ducarouge, Marjolaine Pelissier-Rota, Michèle Lainé, Nadine Cristina, Yvan Vachez, Jean-Yves Scoazec, Bruno Bonaz, Muriel Jacquier-Sarlin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3832608?pdf=render