Gene expression profiling of ampullary carcinomas classifies ampullary carcinomas into biliary-like and intestinal-like subtypes that are prognostic of outcome.

Adenocarcinomas of the ampulla of Vater are classified as biliary cancers, though the exact epithelium of origin for these cancers is not known. We sought to molecularly classify ampullary adenocarcinomas in comparison to known adenocarcinomas of the pancreas, bile duct, and duodenum by gene express...

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Main Authors: Michael J Overman, Jiexin Zhang, Scott Kopetz, Michael Davies, Zhi-Qin Jiang, Katherine Stemke-Hale, Petra Rümmele, Christian Pilarsky, Robert Grützmann, Stanley Hamilton, Rosa Hwang, James L Abbruzzese, Gauri Varadhachary, Bradley Broom, Huamin Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3679143?pdf=render