Differential microRNA Profile in Operational Tolerance: A Potential Role in Favoring Cell Survival

Differential microRNA Profile in Operational Tolerance: A Potential Role in Favoring Cell Survival

Background: Operational tolerance (OT) is a state of graft functional stability that occurs after at least 1 year of immunosuppressant withdrawal. MicroRNAs (microRNA) are small non-coding RNAs that downregulate messenger RNA/protein expression of innumerous molecules and are critical for homeostasi...

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Bibliographic Details
Main Authors: Amanda Cabral, Darlan da Silva Cândido, Sandra Maria Monteiro, Francine Lemos, David Saitovitch, Irene L. Noronha, Letícia Ferreira Alves, Murilo Vieira Geraldo, Jorge Kalil, Edecio Cunha-Neto, Ludmila Rodrigues Pinto Ferreira, Verônica Coelho
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Immunology
Subjects:
kidney transplantation
operational tolerance
immunoregulation
chronic rejection
microRNAs
cell death
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00740/full

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https://www.frontiersin.org/article/10.3389/fimmu.2019.00740/full

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