The Central Role of Cytochrome P450 in Xenobiotic Metabolism—A Brief Review on a Fascinating Enzyme Family

Human Cytochrome P450 (CYP) enzymes constitute a superfamily of membrane-bound hemoproteins that are responsible for the metabolism of a wide variety of clinically, physiologically, and toxicologically important compounds. These heme-thiolate monooxygenases play a pivotal role in the detoxification...

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Bibliographic Details
Main Authors: Francisco Esteves, José Rueff, Michel Kranendonk
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Journal of Xenobiotics
Subjects:
Online Access:https://www.mdpi.com/2039-4713/11/3/7