QSAR and docking studies of coumarin derivatives as potent HIV-1 integrase inhibitors
Human immunodeficiency virus integrase (HIV-1IN) is an emerging and potential drug target for anti-HIV therapy. It is an enzyme essential for 3′ processing and integration step in the life cycle of HIV. In the present study a series of coumarin derivatives (containing 26 compounds) as HIV-1IN inhibi...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2017-02-01
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| Series: | Arabian Journal of Chemistry |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1878535213000270 |