The different modes of binding of the dust mite allergens, Der f 7 and Der p 7, on a monoclonal antibody WH9 contribute to the differential reactivity

Background: Der f 7 and Der p 7 are important house dust mite allergens. An IgE-binding inhibition monoclonal antibody WH9 reacts ten folds stronger against Der p 7 than to Der f 7. The purpose of this study is to identify the antigenic determinant(s) and the structural basis of Der f 7 recognize by...

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Bibliographic Details
Main Authors: Hsiao-Yun Tai, Jia-Kai Zhou, Chang-Ching Yeh, Ming F. Tam, Sheh-Yi Sheu, Horng-Der Shen
Format: Article
Language:English
Published: Elsevier 2018-08-01
Series:Journal of Microbiology, Immunology and Infection
Online Access:http://www.sciencedirect.com/science/article/pii/S1684118217300968