Increased Insulin Sensitivity and Distorted Mitochondrial Adaptations during Muscle Unloading

Increased Insulin Sensitivity and Distorted Mitochondrial Adaptations during Muscle Unloading

We aimed to further investigate mitochondrial adaptations to muscle disuse and the consequent metabolic disorders. Male rats were submitted to hindlimb unloading (HU) for three weeks. Interestingly, HU increased insulin sensitivity index (ISI) and decreased blood level of triglyceride and insulin. I...

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Bibliographic Details
Main Authors: Shuzhe Ding, Wei Guo, Liu Ji, Zhengtang Qi, Yuan Zhang
Format: Article
Language:English
Published: MDPI AG 2012-12-01
Series:International Journal of Molecular Sciences
Subjects:
mitochondrial
insulin sensitivity
pyruvate dehydrogenase kinase 4
hindlimb unloading
skeletal muscle
Online Access:http://www.mdpi.com/1422-0067/13/12/16971

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http://www.mdpi.com/1422-0067/13/12/16971

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