Cerebrovascular pathology during the progression of experimental Alzheimer's disease

Cerebrovascular pathology during the progression of experimental Alzheimer's disease

Clinical and experimental evidence point to a possible role of cerebrovascular dysfunction in Alzheimer's disease (AD). The 5xFAD mouse model of AD expresses human amyloid precursor protein and presenilin genes with mutations found in AD patients. It remains unknown whether amyloid deposition d...

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Bibliographic Details
Main Authors: Patrizia Giannoni, Margarita Arango-Lievano, Ines Das Neves, Marie-Claude Rousset, Kévin Baranger, Santiago Rivera, Freddy Jeanneteau, Sylvie Claeysen, Nicola Marchi
Format: Article
Language:English
Published: Elsevier 2016-04-01
Series:Neurobiology of Disease
Subjects:
CAA
Microvascular inflammation
Alzheimer
5xFAD
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996116300018

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http://www.sciencedirect.com/science/article/pii/S0969996116300018

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