The role of the microRNA-146a/complement factor H/interleukin-1β-mediated inflammatory loop circuit in the perpetuate inflammation of chronic temporal lobe epilepsy

The role of the microRNA-146a/complement factor H/interleukin-1β-mediated inflammatory loop circuit in the perpetuate inflammation of chronic temporal lobe epilepsy

Increasing evidence indicates that neuroinflammation plays a crucial role in the pathogenesis of temporal lobe epilepsy (TLE). However, it is unclear how the perpetuate inflammation develops. Some recent studies have suggested the possible involvement of microRNA-146a (miR-146a) in the modulation of...

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Bibliographic Details
Main Authors: Tao-Ran Li, Yan-Jie Jia, Chao Ma, Wen-Ying Qiu, Qun Wang, Xiao-Qiu Shao, Rui-Juan Lv
Format: Article
Language:English
Published: The Company of Biologists 2018-03-01
Series:Disease Models & Mechanisms
Subjects:
Temporal lobe epilepsy
Inflammation
Interleukin-1β
Complement factor H
MicroRNA-146a
Online Access:http://dmm.biologists.org/content/11/3/dmm031708

Internet

http://dmm.biologists.org/content/11/3/dmm031708

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