Mesenchymal Cells Support the Oncogenicity and Therapeutic Response of the Hedgehog Pathway in Triple-Negative Breast Cancer
The paracrine interaction between tumor cells and adjacent stroma has been associated with the oncogenic activity of the Hedgehog (Hh) pathway in triple-negative breast tumors. The present study developed a model of paracrine Hh signaling and examined the impact of mesenchymal cell sources and cultu...
Main Authors: | Ana M. Reyes-Ramos, Karla P. Ramos-Cruz, Nelson J. Rodríguez-Merced, Michelle M. Martínez-Montemayor, Nelson D. Franqui-Ríos, Jan P. Ríos-Grant, Andrea Flores, Gerónimo Maldonado-Martínez, Wandaliz Torres-García, Maribella Domenech |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-10-01
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Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/11/10/1522 |
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